Qcafé

This establishment operates as a café in the afternoon and turns up the music at night to operate as a bar. It is frequented by young Czechs, but there is also a mix of slightly older men as well. The place has a pretty friendly atmosphere and all the service staff speak enough English to get by. The servers are welcoming and friendly. Sometimes they may come off as a little abrupt, but that is due in a large part to the language barrier.
Qcafe is laid out in two floors. The ground floor is where the bar is located and is usually the most popular floor. This floor also happens to be the smoking floor so expect medium to heavy smoke especially during the evening hours. There is a basement floor below which has comfortable tables to sit around. This floor also serves as a small exhibit and there is artwork for sale hung up around the circumference of the room. No one usually goes down to the basement floor until the ground floor is at capacity.
A couple last few notes. Make sure to come with friends, because although most of the young Czechs knew basic English they are typically more reserved with foreigners and you will have a difficult time striking up a conversation with them. If you come alone you will feel like an outsider. Secondly, the wifi is unusually speedy for Prague standards, so your laptop/​smartphone should feel right at home here. Enjoy!

A neat small reasonably priced rainbow colored café in a quiet place in the center of Prague. The coffee I had (long doppio) was great and it came with a bit of tap water, as it should. They also have some homemade juices and one of the best Czech beer brands Svijany. It has space for both non-​smokers (downstairs) and smokers (quite well air-​conditioned). The music ranges from electronic to jazz and the level easily allows for conversation.